Biochemie (Fach) / Schriftliche Endprüfung (Lektion)

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• What type of bond can be found between complementer bases of the two DNA strands? A. Disulphide bonds B. Phosphodiester bonds C. Van der Waals binding forces D. Each of the answer a) - c) is false D. Each of the answer a) - c) is false
• Which of the following lists shows the components of lecithin? A. Phosphatidic acid + serine B. Glycerol + 2 fatty acids + phosphate + choline C. Diacyl-glycerol + phosphate + cholamine D. Each answer a) - c) is false B. Glycerol + 2 fatty acids + phosphate + choline
• Which of the following lists shows the components of cephalin? A. Phosphoatidic acid + serine B. Glycerol + 2 fatty acids + phosphate + choline C. Diacyl-glycerol + phosphate + cholamine D. Each answer a) - c) is false C. Diacyl-glycerol + phosphate + cholamine
• What type of curve describes the connection between substrate concentration and enzyme activity, if the enzyme is not allosterically regulated? A. Hyperbolic saturation curve B. Exponential curve C. Sigmoidal curve D. Symmetric bell curve A. Hyperbolic saturation curve
• Which of the following statements is false from answer a) - c) concerning membrane forming "cis" unsaturated fatty acids? A. Increased proportion causes increased membrane rigidity B. Oleic acid is one of them C. They may occur in glycerol phosphatids and sphingolipids too D. Neither of answers a) - c) is false A. Increased proportion causes increased membrane rigidity
• It increases enzyme activity: A. Connection of the positive allosteric effector to the substrate binding site B. Disconnection of the negative allosteric effector from the allosteric effector binding site C. Increasing the concentration of competitive inhibitor D. Each answer a) - c) is true B. Disconnection of the negative allosteric effector from the allosteric effector binding site
• Which of the following statements is true from answer a) - c) concerning facilitated diffusion? A. Glucose is transported on the basolateral side of the enterocytes by this transport mechanism B. Transporter (carrier molecule) is required C. Energy is not needed D. Each answer a) - c) D. Each answer a) - c)
• What happens to the red blood cell if getting in a saline solution of 0.3% concentration? A. Red blood cell disintegrate (membrane disruption, hemolysis) B. Red blood cells shrink (plasmolysis) C. The fate of red blood cells depends mainly on the pH of the milieu D. There is no change observed A. Red blood cell disintegrate (membrane disruption, hemolysis)
• Which of the following proteins has quaternary structure? A. Collagen B. Lactate dehydrogenase C. ß-Keratin D. None of the proteins a) - c) has quaternary structure B. Lactate dehydrogenase
• Which of the following proteins belong(s) to the group of storage proteins? A. Succinate dehydrogenase B. Actin C. Casein D. Each answer a) - c) is right C. Casein
• Which property of the enzyme is determined by the catalytic center? A. Reaction specificity B. Substrate specificity C. The optimal temperature for the operation of enzyme D. Each answer a) - c) is false A. Reaction specificity
• Which of the following statements is false from answer a) - c) concerning allosteric enzyme inhibition? A. The inhibitor attaches to the allosteric effector binding site B. The structure of the substrate and inhibitor is typically similar C. Concentration changes of the substrate do not influence the degree of inhibition D. Each answer a) - c) is false B. The structure of the substrate and inhibitor is typically similar
• Which of the following enzymes belongs to the enzyme class oxidoreductases? A. Phosphoglucomutase B. DNA ligase C. Amylase D. Each answer a) - c) is false D. Each answer a) - c) is false
• Which of the following molecules is built up from thymine + desoxy-ribose + 2 phosphate groups? A. Desoxy-thymidine B. dTDP C. dTTP D. Each answer a) - c) is false B. dTDP
• The transcription of what type of RNA is done by DNA polymerase I in eukaryotes? A. mRNA and snRNA B. tRNA and rRNA C. rRNA D. Each answer a) - c) is false C. rRNA
• Why is the process of DNA replication semiconservative? A. The duplicated genetic substance contains only newly formed DNA B. One DNA molecule of the duplicated genetic substance contains only original, the other DNA contains only new strands, produced in the process of replication C. Both DNA molecules of the duplicated genetic substance have one original and one new strand, produced in the process of replication D. Each answer a) - c) is false C. Both DNA molecules of the duplicated genetic substance have one original and one new strand, produced in the process of replication
• Which of the statements a) - c) is false concerning replication? A. The main repair enzyme is DNA polymerase B in eukaryotes B. Elongation of the chain happens by the DNA polymerase I in prokaryotes C. Elongation on the leading strand of DNA happens in the direction of 5' -> 3' D. None of the statements a) - c) is false B. Elongation of the chain happens by the DNA polymerase I in prokaryotes
• Which of the answers a) - c) is true for a transformed host cell containing recombinant plasmid, if the cleavage site of the used restriction endonuclease is in the ampicillin resistance gene? A. The cell can not be cultured on a medium containing ampicillin B. The cell can be cultured on a medium containing ampicillin too C. The cell can be cultured on a medium containing ampicillin only D. Each answer a) - c) is false A. The cell can not be cultured on a medium containing ampicillin
• The oxidation of which of the following molecules covers the majority of the energy needs of the liver? A. Glucose B. Fatty acids C. Amino acids D. Each answer a) - c) is false B. Fatty acids
• Which of the following cells is/are able to produce hyaluronidase? A. Sperms B. Muscle cells C. Nerve cells D. Each answer a) - c) is false A. Sperms
• If during the operation of Na-K-pump 2 ATP molecules are hydrolyses, how many K+ ions can be pumped in by the cell by using up this released energy? A. 2 B. 4 C. 6 D. Each answer a) - c) is false B. 4
• Which of the following is necessary for the initiation of transcription in prokaryotes? A. DNA-dependent B. Sigma factor C. DNA template D. Each molecule a) - c) is necessary D. Each molecule a) - c) is necessary
• What is code? A. The triple units of bases (nucleotides) found on the sense (coding) strand of DNA B. The triple units of bases (nucleotides) found on the mRNA C. The triple units of amino acids of protein produced from mRNA D. The short segment of one of the loop of tRNA A. The triple units of bases (nucleotides) found on the sense (coding) strand of DNA
• What is non-sense mutation? A. The frame shift B. That type if mutation, where the change of nucleotide results in the change of amino acids C. That type of mutations, where the new triplet formed does not encode amino acid D. Each answer a) - c) is false C. That type of mutations, where the new triplet formed does not encode amino acid
• What is "5' capping"? A. Excision of introns during the maturation of mRNA B. 7-methyl-guanosine cap is attached to the 5'end of mRNA C. Poly-A-tailing on the 3'end of mRNA D. Each answer a) - c) is false B. 7-methyl-guanosine cap is attached to the 5'end of mRNA
• Which of the following intermediary product is formed during the activation of amino acids? A. Aminoacyl-mRNA B. tRNA-AMP C. Aminoacyl-AMP D. Each answer a) - c) is false C. Aminoacyl-AMP
• What is the function of the P binding site of the ribosomal large subunit in eukaryotes? A. Binding of methionyl-tRNA, later of peptide-tRNA B. Binding of tRNA transporting the new, be built on amino acid C. This is the binding site of RNA polymerase II D. Each answer a) - c) is false A. Binding of methionyl-tRNA, later of peptide-tRNA
• What is the function of the DHU loop of tRNA A. Binding of aminoacyl-tRNA synthetase B. Binding to the ribosomal large unit C. Binding of amino acids to the CCA sequence of the 3' end of tRNA D. Each answer a) - c) is false A. Binding of aminoacyl-tRNA synthetase
• Which of the following processes is catalyzed by translocate during the elongation of translation? A. Translocation of peptide-tRNA from A to P binding site B. Translocation of the peptide chain being elongated onto the aminoacyl-tRNA on the A binding site and formation of peptide bonds C. Binding of the new aminoacyl-tRNA to the A binding site D. Each answer a) - c) is false A. Translocation of peptide-tRNA from A to P binding site
• Which of the following is necessary for the DNA polymerase III? A. Okazaki-fragments B. Ribonucleoside triphosphate (NTP's) C. Template DNA-strand D. Each answer a) - c) is true D. Each answer a) - c) is true
• Which of the following is necessary for the operation of cytochrome P450 enzymes? A. NAD+ B. NADP+ C. Biotin D. Each cofactor a) - c) is needed B. NADP+
• Which of the following is necessary for reverse transcription? A. Restriction endonuclease B. Olygo-T primer C. DNA dependent DNA polymerase D. Each answer a) - c) is true B. Olygo-T primer
• Which of the following fatty acids belongs to the class omega 3? A. Oleic acid B. Linoleic acid C. Linolenic acid D. Each answer a) - c) is false C. Linolenic acid
• Which is a ketose? A. Glucose B. Fructose C. Galactose D. Each answer a) - c) is true B. Fructose
• In which part of the cells are enzymes of respiratory chain found? A. Mitochondria B. Nucleus C. Cytoplasm D. Ribosome A. Mitochondria
• Which of the following amino acids contains the most nitrogen? A. Methionine B. Arginine C. Glutamine D. All the same B. Arginine
• Which of the following are co-factors? A. NADP B. NAD C. PALP D. All of them D. All of them
• How much will the intracellular weight be if a dog is 12 kg? A. 1 kg B. 3 kg C. 4 kg D. 8 kg D. 8 kg
• Which one of these has oxygen attached in the side group? A. Asparagine B. Glutamate C. Tyrosine D. All D. All
• Which one of these uses facilitated diffusion? A. Glucose B. Urea C. Oleic acid D. None of them A. Glucose
• Which muscle is continuous acting? A. White - fast twitch fiber (short lasting) B. Red - slow twitching (continuous) C. Transition D. All of them B. Red - slow twitching (continuous)
• Which one is an omega 3? A. Oleic acid B. Linoleic acid C. Linolenic acid D. Arachidonic acid E. None of them C. Linolenic acid
• Which one has a restriction endonuclease? A. Bacteria B. Virus C. Bacteria phage D. None of the above A. Bacteria
• What do you need to finish a protein? A. GTP B. ATP C. snRNA D. Neither of them A. GTP
• Which one of these needs energy? A. Binding of peptide tRNA to P site B. Peptidyl translocate enzyme C. Removal of tRNA from ribosome D. All of them D. All of them

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