Deletion of E1B-55K ➔ cannot inhibit p53 ➔ virus is attenuated in normal cells - in cells that are p53 deficient (cancer cells!) --> virus can replicate - head and neck cancer treatment combined with chemotherapy

Virology (MD PhD) (Fach) / Henni (Lektion)

Henni

Diese Lektion wurde von estoffel erstellt.

Lektion lernen

ONYX-015 or H101 Deletion of E1B-55K ➔ cannot inhibit p53 ➔ virus is attenuated in normal cells - in cells that are p53 deficient (cancer cells!) --> virus can replicate - head and neck cancer treatment combined with chemotherapy