Neuro (Subject) / Prüfung MolMed (Lesson)

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  • Which contents are encoded by declerative memories? personal event (episodic memory, time line)  learning new facts (semantic memory, language)  explicit expression of memory (free recall)
  • Which brain areas exhibit ongoing neurogenesis in the adult mammalian brain? dentate gyrus of the hippocampus, subventricular zone (SVZ), olfactory bulb
  • Which phase of memory formation are modulated by sleep? memory consolidation
  • Which animal tests are generally used to investigate spatial memory? Different mazes: -T&Y maze -Morris water maze
  • Which step of memory formation is affected when a drug given after training disrupts lomg-term, but not short-term memory? Disrupts Consolidation (processes that stabilize an engram after its initial acquisition
  • Which is the main output nucleus of the amygdala complex? central nucleus of the amygdala (CeA) [Google/Wikipedia] mediale Teil des centralen nucleus (CeM)
  • Which are characteristic featuers of anxiety? Nature: -state of chronic apprehension about future harm -distal or potential threats (predator odor) Response: -hyperarousal, avoidance and risk assessment -sustained/long duration Anatomy: -BNST -Hippocampus -Hypothalamus
  • Which are characteristic features of fear? Nature: -response to an impending identifiable danger -behaviors elicited by actual danger (presence of a predator) Response: -intense motivation to escape =fight or flight -aversive states: phasic/short duration Anatomy: -Amygdala -Hyppocampus -PFC .-Hypothalamus
  • What are characteristic symptoms of the Klüver-Bucy Syndrome? =damage of the temporal lobe  Tameness: loss of fear/anxiety or diminished aggression Dietary changes: indiscriminated dietary behavior  altered sexuality: greatly increased autoerotiy, homosexual or heterosexual activity or inappropiated sexual object choice  Hypermetamorphosis: tendency to attend to and react to every visual stimulus Hyperorality: tendency to examine all objects by mouth  phsychic blindness: visual agnosia
  • What is characteristic for interneurons of the basolateral amygdala (BLA)? 80% pyramidal neurons  20% interneurons  excitatory pyramidal neurons (glutamate) are under tight inhibitory control of interneurons (GABA)