Medical Microbiology (Subject) / Environments (Lesson)

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• Skin: conditions dry, acidic, salty, aerobic (pores and folicles may be anoxic)
• Skin: species S.epidermidis, S.aureus
• Skin: pimples 1.Dead cells block an oil gland and form blackheads 2.Bacteria start decomposing material inside 3.propionic acid is produced, inflammatory -> white head produced
• Nasopharynx: Species Staphylococcus aures, Streptococcus pneumoniae
• Oral Cavity:Species Streptococcus salivarius, S.mutans, S.Sobrinus, S.sanguines
• Oral Cavity: conditions before eruption of teeth: aerobic after eruption of teeth: anaerobic
• Oral cavity: Dental plaque 1. glycoproteins form film on teeth -> specific binding of cocci 2. Sucrose -> glucose and fructose 3. fructose fermented into lactic acid 4. glucose into 1-4-alpha-link (not cleavable by us) 5.Biofilm formed, lactic acid erodes enamel (fluoride changes hydroxyapatite to fluroapatite)
• small intestine; colon: Species E.coli, Enterococci
• Small intestine, colon: diseases obesity, inflammatory bowel disease
• Urogenital tract:Vagina species before puberty pH neutral, S.epidermidis after puberty pH acidic, L.acidophiles
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• Urogenital tract: urethra species S.epdidermidis, enterococci diptheroides

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