3
antibiotics (Subject) / Carbapenems (Lesson)
- active substances Imipenem (+ Cilastatin) Cilastatin -> inactivates dihydropeptidase (which would normally metabolize imipenem in the kidney straight away) -> longer half-life
- Spectrum extemely broad spectrum: Gram + Gram -
- Indications only in life-threatening situations and multi-resistant infections -> last-resort antibiotic