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Medizin (Subject) / Antimykotika (Lesson)

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• Polyene Ergosterolbindung -> Poren in Membran Amphotericin B und Nystatin
• Azole Inhibition 14alpha-Lanosterin-Demethylase -> Stopp Ergosterolsynthese CYP-Metabolisierung Fluconazol, Vorriconazol, Traconazol, Posaconazol
• Echinocandine Inhibition beta-1,3-Glucan-Synthese -> Zellwandschädigung Caspofunging, Micafungin, Aniculafungin
• Alkylamine Hemmung Squalenepoxidase -> kein Ergosterol

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