USMLE (Fach) / Hematology and Oncology (Lektion)
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ABO hemolytic disease of the newborn
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Type O mother with a type A, B, or AB fetus
- Pre-existing maternal anti-A and/or anti-B igG antibodies cross placenta → HDN in the fetus
- Mild jaundice in the neonate within 24 hours of birth. - Usually less severe than Rh HDN.
- Treatment: phototherapy, exchange transfusion
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