Protazoa.- Transmission: Tsetse fly, a painful bite (vs Trypanosoma cruzi)

African sleeping sickness – enlarged lymph nodes, recurring fever (due to antigenic variation), meningoencephalitis, somnolence, coma.- Two subspecies: Trypanosoma brucei rhodesiense/gambiense

Diagnosis: Trypomastigote in blood smear

Treatment: Suramin for blood-borne disease or melarsoprol for CNS penetration ("I am sure melanin helps with sleep.")