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Biochemistry (Fach) / Introduction (Lektion)
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- early earth conditions stanley Miller experiment: compounts: NH3, H2S, CO, CO2, CH4, N2, H2, H2O with lightning amino acids could form
- Exergonic reaction spontaneous, energy release
- Endergonic reaction unfavourable, needs energy
- amount of energy released per mol ATP 30.5 kJ/mol ATP
- functions of water in the human body solvent, transporter, homeostasis
- how is ATP formed? esterification and two anhydride reactions
- Henderson-Hasselbach equation pH = pKa + log [conjugate base]/[weak acid]
- buffer system in cells H2PO4(-)/ HPO4(2-)
- Hyperventilation vs Hypoventilation reaction: CO2 + H2O -> H+ + HCO3- Hyperventialtion leads to an increased blood pH, hypoventilation in a decease
- Buffer system in blood Bicarbonate: H2CO3 / HCO3-
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- pI value calculation pI = (pKa1 + pKa2) / 2 if three or more pKa´s take the two which deviate the least from zero net charge
- Bohr effect oxygen release and CO2/H+ uptake when high H+ present oxygen uptake when high O2 present and low H+
- how does foetal haemoglobin differ from the mothers? altered 2,3- bisphosphogylcerate
- prion 28 kda infectious particle natural glycoprotein in nervous cell membranes bse, scapie, creutzfeldt-jakob, kuru