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Medical Microbiology (Fach) / Good, Bad & Ugly (Lektion)
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- Human Microbiome Sum of all micros in and on us
- tissue tropism prefer certain type of cells in the body
- gnototbiotic organism grown without any microorganisms
- positiv effects for MO supply of nutrients, stable environment, constant temp and PH, protection, transport
- positive effect on us synthesis of vitamins, competition for pathogenic organism, killing non native toxins, stimulation of tissue development, stimulation of cross reactive anti body production
- Disease infection with subsequent symptons
- Asymptotic carrier reservoir for pathogenic organisms
- infectious dose minimal number of pathogens to cause infection
- Bacterimia presence of pathogens in blood
- Sepsis pathogens able to multiply in blood
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- pathogenicity ability to cause an infection or disease (species specific)
- virulence degree of pathogenicity (strain specific)
- lethal dose 50 Kill 50% of organisms affected
- infectious dose 50 infect 50% of organisms affected
- Koch Postulates 1.presence in all sick people 2.pure culture possible 3.same symptons of disease 4.isolated same pure culture