USMLE (Fach) / Infectious diseases (Lektion)

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Pathology

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  • Vertical transmission 1. Placental-fetal transmission- rubella infection during first trimester --> heart malformation, cataracts, deafness 2. Transmission during birth- gonococcal, chlamydial conjunctivitis 3. Postnatal transmission ...
  • Pathogens resistant to intracellular killing in phagocytes ... - mycobacteria - Listeria - Cryptococcus neoformans - leishmania - trypanosomes - toxoplasmas
  • Genes for toxins found in plasmids - cholera - diphtheria - botulism
  • Exotoxins - Enzymes eg: exfoliative toxins produced by S. aureus cause staphylococcal scalded skin syndrome, SSSS, by degrading proteins that hold keratinocytes together) - Toxins that alter intracellular signaling ...
  • STIs Viruses- Herpes simplex virus --> neonatal herpes- Hepatitis B virus --> hepatitis- Human papillomavirus --> condyloma acuminatum- HIV --> AIDS Chlamydia trachomatis --> lymphogranuloma venereum Bacteria- ...

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