Pathologie (Fach) / Geschlechtsorgane (Lektion)

Vorderseite Phyllodes tumor
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Rare fibroepithelial tumor with histology similar to that of fibroadenoma.

Epidemiology:- 1% of all breast tumors- Most commonly benign- Peak incidence: 40-50 years

Clinical features:- Painless, smooth, multinodular lump in the breast- Variable growth rate: may grow slowly over many years, rapidly, or have a biphasic growth pattern- Average size 4-7 cm

Diagnosis:- Ultrasound and mammogram findings are similar to fibroadenoma, but phyllodes tumors tend to be larger and grow faster than fibroadenoma- Despite typically being a benign lesion, a suspected phyllodes tumor should be considered a suspicious mass until proven otherwise.- When phyllodes tumor is suspected (based on clinical or imaging findings) → core biopsy → Leaf-like architecture with papillary projection of epithelium-lined stroma and varying degrees of atypia and hyperplasia

Treatment: Surgical excision- In case of recurrence: total mastectomy

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