Pathologie (Fach) / ORL (Lektion)

Vorderseite Pleomorphic adenoma
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Epidemiology: F > MPeak incidence: 40-60 years

Accounts for 85% of benign salivary gland tumors.

Etiology: Ionizing radiation, environmental/occupational exposure (eg, rubber manufacturing, cosmetologists, nickel compound exposure)

Location: mostly the parotid gland (∼80% of cases)

Symptoms: Gradual and painless unilateral swelling of the parotid gland- Robust, movable tumor

Diagnostics:- Ultrasound: diagnostic method of choice in salivary gland tumors- MRI: sharply limited, lobulated hyperintense mass- Histology: → Mixed cellular constitution with myoepithelial cells and chondroid tissue→ Cytokeratin is expressed immunohistochemically

Complications: Recurs if incompletely excised; rarely malignant degeneration (∼5% of cases).

Treatment: Superficial parotidectomy

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