5 types: - Hepatitis A: Contaminated water; travelers- Hepatitis E: Undercooked seafood, water, fulminant in pregnant women- Hepatitis C: Childbirth, sex, drug-users; chronic; diagnose with RNA level- Hepatitis B: Childbirth, sex, drug-user; chronic in 20% but increased in children; associated with HCC- Hepatitis D: Can only infect if host has HBV

Symptoms:- Fever, malaise, nausea- Hepatomegaly, pain- Jaundice

Hepatocytes undergoing apoptosis = Councilman bodies

Diagnosis:- ALT > AST, ↑ unconjugated and conjugated bilirubin → brown urine (urobilinogen)- Atypical lymphocytosis (large from antigen stimulation)

If it lasts longer than 6 months → chronic