↓ T-cells:- Bacteria: Sepsis- Viruses: CMV, EBV, JC virus, VZV, chronic infeciton with respiratory/GI viruses- Fungi/parasites: Superficial, local Candida, PCP, Cryptococcus

↓ B-cells:- Bacteria: Encapsulated (Pseudomonas, Streptococcus pneumoniae, Haemophilus influenzae type b, Neisseria meningitidis, E coli, Salmonella, Klebsiella pneumoniae, group B Streptococcus)- Viruses: Enteroviral encephalitis, poliovirus (live vaccine contraindicated)- Fungi/parasites: GI giardiasis (no IgA)

↓ Granulocytes:- Bacteria: Staphylococcus, Burkholderia, Pseudomonas, Serratia, Nocardia- Viruses: N/A- Fungi/parasites: Systemic Candida, Aspergillus, Mucor