USMLE Step 2 (Fach) / Dermatology (Lektion)

Vorderseite Basal cell carinoma
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Epidemiology:- Most common malignant skin tumor- Sex: ♂ > ♀ (∼ 2:1)

Etiology:- Sun exposure- Skin types I and II (people with light complexions, red hair, and who sunburn easily)- Nevoid basal-cell carcinoma syndrome (Gorlin syndrome)

Clinical features- Localization: Eyelid, nose- Pearly, indurated and nodular lesion with rolled border that is usually nontender- Central depression (crater) with ulceration- Slowly growing over months to years; Very rarely metastasizes

Subtypes: Nodular and superficial

Diagnostics: - Dermoscopy: initial clinical evaluation of suspected BCC lesions- Excisional biopsy (full-thickness biopsy): Most accurate assessment of the histologic subtype of the tumor

Treatment: - Surgical excision of BCC with a safety margin of surrounding healthy tissue- Mohs micrographic surgery: The tumor is removed layer by layer, and each layer is examined for tumor cells.

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