A poxvirus infection that is most common in young children and in AIDS patients. It is spread by direct skin-to-skin contact (sport, sex) or sharing infected clothing or towels.

Risk factors: immunosuppression, active atopic dermatitis (in children), hot and humid climates, crowded living conditionsSuspect AIDS if large, persistent, widespread lesions appear on an adult!

History/PE:- Presents as tiny flesh-colored dome-shaped waxy papules, frequently with central umbilication. In children, lesions are found on the trunk, extremities, or face. In adults, they are most commonly found on the genitalia and in the perineal region. Typically spares palms and soles.- Lesions are asymptomatic.

Diagnosis: Clinical

Treatment:- Spontaneous remission usually happens within 6-9 months (thus treatment often unnecessary).- Consider treatment for sexually transmitted cases, immunocompromised individuals, and/or to reduce autoinoculation or transmission.- Cryotherapy is often the first-line treatment for adolescents and adults as it is better tolerated than in children.- Curettage