Dimorphic fungus.

Location: Eastern and Central US

Pathology: Broad-based budding of Blastomyces (same size as RBCs)

Symptoms:- Inflammatory lung disease- Can dissiminate to skin/bone- Verrucous skin lesions can simulate SCC- Forms granulomatous nodules

Treatment: Fluconazole/itraconazole for local infection; amphotericin B for systemic disease.