USMLE (Fach) / Biochemistry - Genetics (Lektion)

Vorderseite Hardy-Weinberg population genetics
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If a population is in Hardy-Weinberg equilibrium and if p and q are the frequencies of seperate alleles, then p2 + 2pq + q2 = 1 and p + q = 1, which implies that:

p2 = frequency of homozygosity for allele pq2 = frequency of homozygosity for allele q2pq = frequency of heterozygosity

The frequency of an X-linked recessive disease in males = q and in females q2

Hardy-Weinber assumptions include:- No mutation occurring at the locus- Natural seleciton is not occuring- Completely random mating- No net migration

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