USMLE (Fach) / Biochemistry - Genetics (Lektion)
Vorderseite
Adenosine deaminase deficiency
Rückseite
- autosomal recessive
- excess ATP accumulate in red cells and inhibit ribonucleotide reductase --> decreased production of other precursors for DNA synthesis --> ↓ lymphocyte count
- major cause of SCID (severe combined immunodeficiency), because T-cells are unable to develop
Diese Karteikarte wurde von estoffel erstellt.