Pathologie (Fach) / Muskuloskeletal (Lektion)

Vorderseite Benign bone tumors
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Osteochondroma- Most common benign bone tumor.- Males < 25 years old.- Metaphysis of long bones.- Lateral bony projection of growth plate (continuous with marrow space) covered by cartilaginous cap.

Osteoma- Middle age.- Surface of facial bones.- Associated with Gardner syndrome.

Osteoblastoma- Vertebrae.- Similar histology to osteoid osteoma. - Larger size (> 2 cm), pain unresponsive to NSAIDs.

Chondroma- Medulla of small bones of hand and feet.- Benign tumor of cartilage.

Giant cell tumor- 20-40 years old.- Epiphysis of long bones (often in knee region).- Locally aggressive benign tumor. - Neoplastic mononuclear cells that express RANKL and reactive multinucleated giant (osteoclast-like) cells.- “Soap bubble” appearance on x-ray.

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