USMLE (Fach) / Biochemistry - Molecular, Cellular, Techniques (Lektion)
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Histone methylation/acetylation
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Histone methylation: Usually causes reversible transcriptional suppression, but can also cause activation depending on the location of methyl groups.
Histone acetylation: Relaxes DNA coiling, allowing for transcription.
Methylation makes DNA mute.Acetylation makes DNA active.
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