USMLE (Fach) / Biochemistry - Molecular, Cellular, Techniques (Lektion)

Vorderseite DNA methylation
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Changes the expression of a DNA segment without changing the sequence.

Involved with genetic imprinting, X-chromosome inactivation, repression of transposable elements, aging, and carcinogenesis.

DNA is methylated in imprinting.Methylation within gene promotor (CpG islands) typically represses gene transcription.

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