USMLE (Fach) / Kaplan - Pathology (Lektion)

Vorderseite Atherosclerosis

Earliest (clinically reversible stage): Fatty streak
- Grossly: yellow intimal streak and characterized
- Microscopically: lipid-laden macrophages (foam cells)

- Stable atheromatous plaques: Dense fibrus cap, small lipid core, less inflammation. Cause chronic ischemia.

- Vulnerable atheromatous plaques: At risk for rupture, thrombosis or embolization due to composition (thin fibrous cap, large lipid core, dense inflammation).

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