USMLE (Fach) / Kaplan - Pathology (Lektion)

Vorderseite Hemolytic uremic syndrome (HUS)

Thrombotic microangiopathy due to endothelial cell damage.

- Occurs mostly in children, typically after a gastroenteritis (typically due to Shiga toxin-producing E coli 0157:H7)

- Abdominal pain, diarhhea
- Microangiopathic hemolytic anemia
- Thrombocytopenia
- Renal failure (more commonly than in TTP)

- Kidneys show fibrin thrombi in the glomeruli

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