USMLE (Fach) / Immunology (Lektion)
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Febrile nonhemolytic transfusion reaction
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Two known mechanisms:- Type II hypersensitivity reaction with host antibodies against donor HLA and WBCs- Induced by cytokines that are created and accumulate during the storage of blood products
Presentation:- Fever- Headaches- Chills- Flushing
Timing: Within 1-6 hours
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