USMLE (Fach) / Pharmacology (Lektion)
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Bioavailability (F)
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Part of the pharmacokinetics.
Fraction of administered drug reaching systemic circulation unchanged.
For IV dose, F = 100%.Orally: F typically <100% due to incomplete absorption and first-pass metabolism.
F = area under the oral curve/area under the IV curveIf doses arent the same F = (area under the oral curve x IV dose)/(area under the IV curve x oral dose)
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