USMLE (Fach) / Pharmacology (Lektion)

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Competitive inhibitors, reversible:- Resemble substrate: Yes- Overcome by ↑ [S]: Yes- Bind active site: Yes- Effect on Vmax: Unchanged- Effect on Km: ↑- Pharmacodynamics: ↓ potency

Competitive inhibitors, irreversible:- Resemble substrate: Yes- Overcome by ↑ [S]: No- Bind active site: Yes- Effect on Vmax: ↓- Effect on Km: Unchanged- Pharmacodynamics: ↓ efficacy

Noncompetitive inhibitors:- Resemble substrate: No- Overcome by ↑ [S]: No- Bind active site: No- Effect on Vmax: ↓- Effect on Km: Unchanged- Pharmacodynamics: ↓ efficacy

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