USMLE (Fach) / Pharmacology (Lektion)
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Lineweaver-Burk plot
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↑ y-intercept, ↓ Vmax.
The further to the right the x-intercept (ie, closer to zero), the greater the Km and the lower the affinity.
Competitive inhibitors cross each other on the y-axis (same Vmax), but is further right on the x-intercept (increase Km).
Noncompetitors have the same x-intercept (no change in Km), but have a steeper curve and cross higher on the y-intercept (lower Vmax).
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