USMLE (Fach) / Pharmacology (Lektion)
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Michaelis-Menten kinetics
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Km is inversely related to the affinity of the enzyme for its substrate.
Vmax is directly proportional to the enzyme concentration.
Most enzymatic reactions follow a hyperbolic curve (ie, Michaelis-Menten kinetics); however, enzymatic reactions that exhibit a sigmoid curve usually indicate cooperative kinetics (eg, hemoglobin).
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