USMLE (Fach) / Embryology (Lektion)
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Kidney embryology
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Pronephros - degenerates
Mesonephros - functions as intermin kidney, later contributes to male genital system
Metanephros - permanent- Ureteric bud: derived from caudal end of mesonephric duct, gives rise to ureter, pelvises, calyces, collecting ducts- Metanephric mesenchyme: ureteric bud interacts with this tissue; interaction induces differentiation and formation of glomerulus through to distal convoluted tubule- Aberrant interaction between these 2 tissues may result in congenital malformations
Ureteropelvic junction - last to canalize --> most common site of obstruction (hydronephrosis) in fetus
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