USMLE (Fach) / Virology (Lektion)
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Paramyxoviruses
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Enveloped, ⊝ ssRNA, non-segmented
Parainfluenza – croup (seal-like barking cough)Mumps, MeaslesRSV – bronchiolitis in babies
- All contain surface F (fusion) protein, which causes respiratory epithelial cells to fuse and form multinucleated cells.
- Palivizumab (monoclonal antibody against F protein) prevents pneumonia caused by RSV infection in premature infants.
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