USMLE (Fach) / Microbiology (Lektion)
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Gardnerella vaginalis
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Pleomorphic, gram-variable rods. Catalase and oxidase negative.
- Involved in bacterial vaginosis (excessive growth of certain anaerobic bacteria in vagina).
- Thin, gray vaginal discharge with a fishy smell; nonpainful (vs vaginitis). Not itchy.- Amine whiff test – mixing discharge with 10% KOH enhances fishy odor.
- Associated with sexual activity, but not sexually transmitted
- Clue cells (vaginal epithelial cells covered with Gardnerella) have stippled appearance along outer margin.
- Treatment: metronidazole or clindamycin
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