USMLE (Fach) / Microbiology (Lektion)
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Klebsiella
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Gram ⊝ rod. - Polysaccharide capsule.- Reservoir: human colon and upper respiratory tract.
- Mucoid, lactose-fermenting colonies on MacConkey agar.- Dark red "current jelly" sputum (blood/mucus)
- Pneumonia: Community-acquired, most often older males, most commonly those with chronic lung disease, alcoholism, or diabetes. Often aspirated.- Nosocomial UTI: from fecal contamination of catheters- Septicemia: in immunocompromised patients, may originate from bowel defect
- Associated with evolution of multidrug resistance (MDR).
Treatment: 3rd generation cephalosporin, fluorochinolones
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