USMLE (Fach) / Biochemistry - Genetics (Lektion)

Vorderseite Glucose 6-Phosphate Dehydrogenase Deficiency
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- X-linked recessive

- hemolytic anemia

- red blood cells contain a large amount of oxygen and are prone to spontaneously generate ROS that damage protein and lipid in the cell.

- In the presence of ROS, hemoglobin may precipitate (Heinz bodies)

- NADPH required by glutathione reductase is supplied by the HMP shunt

- increased resistance to malaria

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